منابع مشابه
Calcitonin substitution in calcitonin deficiency reduces particle-induced osteolysis
BACKGROUND Periprosthetic osteolysis is a major cause of aseptic loosening in joint arthroplasty. This study investigates the impact of CT (calcitonin) deficiency and CT substitution under in-vivo circumstances on particle-induced osteolysis in Calca -/- mice. METHODS We used the murine calvarial osteolysis model based on ultra-high molecular weight polyethylene (UHMWPE) particles in 10 C57BL...
متن کاملStress-induced analgesia.
For over 30 years, scientists have been investigating the phenomenon of pain suppression upon exposure to unconditioned or conditioned stressful stimuli, commonly known as stress-induced analgesia. These studies have revealed that individual sensitivity to stress-induced analgesia can vary greatly and that this sensitivity is coupled to many different phenotypes including the degree of opioid s...
متن کاملCalcitonin-Induced Acute Pancreatitis: A Case-Report
A 68 years old woman was admitted for abdominal pain, acute pancreatitis complicated with peripancreatic fluid collections. She has received steroid treatment during 12 months for pulmonary fibrosis, 60 mg/day Prednisone in the last months. Three weeks before her admission calcitonin treatment was introduced for osteoporotic vertebral fracture. The pancreatitis followed a benign clinical course...
متن کاملOsteoblasts release osteoclasts from calcitonin-induced quiescence.
There is an increasing body of indirect evidence that suggests that the localization and activity of osteoclasts, the major agents of bone resorption, are controlled by osteoblasts. In this paper I provide direct evidence that osteoblasts are indeed able to alter the behaviour of osteoclasts. I used calcitonin (CT) to suppress the cytoplasmic activity of osteoclasts isolated on glass or plastic...
متن کاملThe Role of Hypocretin/Orexin in Stress-Induced Analgesia
Orexin is produced exclusively in the lateral hypothalamus, where it is known to be involved in pain modulation through brain stem. Due to the important role of this peptide in functions such as eating, sleeping and awaking, addiction, it attracted the attention of researchers in medical sciences specially neuroscientists. These hypothalamic peptides play a critical role in arousal in s...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1984
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)62637-5